Yellow fever is preventable by a relatively safe, effective vaccine. The single-dose 'live' vaccine is recommended for people 9 months of age and older. The vaccine becomes protective after 10 days, and provides immunity to a vaccinated individual for 10 years or more. From 1 January through 10 December 2019, a total of 4,189 suspected yellow fever cases were reported from 604 of 774 Local Government Area (LGAs) across all the 36 states and the Federal Capital Territory in Nigeria. Of the total 3,547 samples taken, 207 tested positive for yellow fever by Immunoglobulin M (IgM) in Nigerian network laboratories This conclusion was based on a systematic review of published studies on the duration of immunity after a single dose of yellow fever vaccine, and on data that suggest vaccine failures are extremely rare and do not increase in frequency with time since vaccination (10). The advisory group noted that future studies and surveillance data should death (20 to 50% of serious cases) Yellow fever vaccine is a live, weakened virus. It is given as a single shot. For people who remain at risk, a booster dose is recommended every 10 years. Yellow fever vaccine may be given at the same time as most other vaccines. The most important measure for the prevention of yellow fever is vaccination. In clinical trials, 80%– 100% of vaccine recipients develop protective immunity within 10 days and 99% do so within 30 days. Although the yellow fever vaccine is safe and adverse events are uncommon, contraindications Yellow fever vaccination is recommended for the intended destination, based on yellow fever endemic status at the time of the travel or if an International Certificate of Vaccination is required .

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